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The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars

Mehmet Ihsan Okur, Alpagan Mustafa Yildirim, Bilsev Ince.


Abstract
Background: The development of hypertrophic scars after burns can lead to esthetic as well as functional disorders. The aim of the study was to determine the functional and cosmetic effects of Contractubex® (onion extract, heparin, allantoin) gel applied in burn scar patients after surgery for scar excision and skin grafts.
Patients and Methods: The study included seven male patients who presented to our clinic between 2005 and 2012 for the treatment of hypertrophic burn scar and were administered either single or combined medical hypertrophic scar treatments. Patients who had scars on the right upper extremity were included in group 1 and those with left upper extremity scars in group 2. In group 1, all scars were excised and closed with medium thickness skin graft. After surgery, the onion extract gel was applied to the right upper extremities. In group 2, only surgical treatment was applied. The results were evaluated with Vancouver scar scale.
Results: Vascularity, flexibility, and height of the scars improved significantly in both groups. In addition, hyperpigmentation was observed on the skin grafts of all patients. Scar flexibility was less often observed in patients’ left upper extremities. However, no statistical difference between groups 1 and 2 was found.
Conclusion: Although no significant difference was obtained with Contractubex gel treatment in this study, cosmetic and functional success can be achieved through excision of the scar and use of medium thickness skin graft in patients with upper extremity hypertrophic burn scarring that is resistant to conservative treatments.

Key words: Hypertrophic scar, surgical treatment, onion extract, heparin, allantoin, Vancouver scar scale

 

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How to Cite this Article
Pubmed Style

Okur MI, Yildirim AM, Ince B. The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars. Hand Microsurg. 2014; 3(3): 74-79. doi:10.5455/handmicrosurg.172436


Web Style

Okur MI, Yildirim AM, Ince B. The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars. http://handmicrosurgeryjournal.com/?mno=172436 [Access: April 24, 2018]. doi:10.5455/handmicrosurg.172436


AMA (American Medical Association) Style

Okur MI, Yildirim AM, Ince B. The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars. Hand Microsurg. 2014; 3(3): 74-79. doi:10.5455/handmicrosurg.172436


Vancouver/ICMJE Style

Okur MI, Yildirim AM, Ince B. The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars. Hand Microsurg. (2014), [cited April 24, 2018]; 3(3): 74-79. doi:10.5455/handmicrosurg.172436


Harvard Style

Okur, M. I., Yildirim, A. M. & Ince, B. (2014) The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars. Hand Microsurg, 3 (3), 74-79. doi:10.5455/handmicrosurg.172436


Turabian Style

Okur, Mehmet Ihsan, Alpagan Mustafa Yildirim, and Bilsev Ince. 2014. The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars. Hand and Microsurgery, 3 (3), 74-79. doi:10.5455/handmicrosurg.172436


Chicago Style

Okur, Mehmet Ihsan, Alpagan Mustafa Yildirim, and Bilsev Ince. “The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars.” Hand and Microsurgery 3 (2014), 74-79. doi:10.5455/handmicrosurg.172436


MLA (The Modern Language Association) Style

Okur, Mehmet Ihsan, Alpagan Mustafa Yildirim, and Bilsev Ince. “The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars.” Hand and Microsurgery 3.3 (2014), 74-79. Print. doi:10.5455/handmicrosurg.172436


APA (American Psychological Association) Style

Okur, M. I., Yildirim, A. M. & Ince, B. (2014) The utility of onion extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars. Hand and Microsurgery, 3 (3), 74-79. doi:10.5455/handmicrosurg.172436